Brook Byers is a founding member of Kleiner Perkins Caufield & Byers. A venture capital investor since 1972, Brook has been closely involved with more than 60 new technology-based ventures, many of which have become public companies. He formed the first life sciences practice group in the venture capital profession in 1984 and led KPCB to become a premier venture capital firm in the medical, healthcare and biotechnology sectors. KPCB has invested in and helped build more than 110 life sciences companies that have developed hundreds of products to treat underserved medical needs for many millions of patients.

Brook is on the Board of Overseers of the University of California San Francisco medical campus and hospitals. In 2007, UCSF awarded Brook the UCSF Medal, its honorary degree equivalent. He is also on the Board of Trustees of Stanford University. In 2008, Brook was elected a fellow of the American Academy of Arts and Sciences. In 2009, he received the Lifetime Achievement Award from the National Venture Capital Association. In 2010, he received an honorary Ph.D. from Georgia Institute of Technology.