Connor Landgraf founded Eko while an undergraduate studying bioengineering at the University of California, Berkeley, with the goal of improving monitoring for cardiovascular and pulmonary disease patients through machine learning non-invasive sensors. Eko became the youngest team to receive FDA clearance for a medical device, and Eko technology is used today by more than 4,000 hospitals, health systems, clinics, and practices for cardiac and pulmonary screening. Since its founding, Eko has built the world’s largest database for heart sounds and has successfully put the ears of a trained cardiologist in any clinician’s stethoscope. Connor Landgraf has been named to the Forbes 30 under 30. We discuss how to recognize an opportunity for growth in an industry, persevere through the challenges of finding early investors, and hold onto the core of the company’s mission.